Vitamin B12 occurs in foods that come from animals. Normally, vitamin B12 is readily absorbed in the last part of the small intestine (ileum), which leads to the large intestine. However, to be absorbed, the vitamin must combine with intrinsic factor, a protein produced in the stomach. Without intrinsic factor, vitamin B12 moves through the intestine and is excreted in stool.
Because vitamin B12 is necessary for the formation of mature blood cells, deficiency of this vitamin can result in anemia. The anemia is characterized by abnormally large red blood cells (macrocytes) and white blood cells with abnormal nuclei. Anemia may not develop until 3 to 5 years after the deficiency begins because a large amount of vitamin B12 is stored in the liver.
Vitamin B12 deficiency can cause nerve damage (neuropathy) even when no anemia develops, particularly in people older than 60.
Causes
Vitamin B12 deficiency can result when people do not consume enough vitamin B12 or when the body does not absorb or store enough of the vitamin.
Inadequate Consumption: Vitamin B12 deficiency develops in people who do not consume any animal products (vegans) unless they take supplements. If a vegan mother breastfeeds her infant, the infant is at risk of vitamin B12 deficiency.
Inadequate Absorption: The most common cause of vitamin B12 deficiency is inadequate absorption. The following conditions can cause absorption to be inadequate:
Overgrowth of bacteria in part of the small intestine
Malabsorption disorders
Inflammatory bowel disease
Fish tapeworm infection
Surgery that removes the part of the small intestine where vitamin B12 is absorbed
Drugs such as antacids and metformin Some Trade Names
GLUCOPHAGE
(used to treat diabetes)
Lack of intrinsic factor
Decreased stomach acidity (common among older people)
Intrinsic factor may be lacking because abnormal antibodies, produced by an overactive immune system, attack and destroy the stomach cells that produce intrinsic factor—an autoimmune reaction. Intrinsic factor may be lacking because the part of the stomach where it is produced was surgically removed. Vitamin B12 deficiency due to lack of intrinsic factor causes a type of anemia called pernicious anemia.
Among older people, absorption may be inadequate because stomach acidity is decreased. Decreased stomach acidity reduces the body's ability to remove vitamin B12 from the protein in meat. The vitamin B12 found in vitamin supplements, however, can continue to be well absorbed even in people with decreased stomach acid. For more information be sure to visit http://www.trivitaproduct.info/b12
B-12 ia a very vital vitamin in your health arsonal. Take it daily.
To Your Continued Good Health,
Kim Buchanan
TriVita Business Affiliate 11225081
http://trivitaproduct.info/
http://www.trivitaproduct.info/b12
http://vitamin-b12-supplements.blogspot.com/
Resource:Sublingual B-12 Web Site
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