Pernicious Anemia in Relation to B12 Absorption

New DocumentPernicious Anemia in Relation to B12 Absorption

*Who Is At Risk for Pernicious Anemia?

*Pernicious anemia is more common in people of Northern European and African descent.

*In the United States, older people are at higher risk for the condition. This is mainly due to a lack of stomach acid and intrinsic factor, which prevents the small intestine from absorbing vitamin B12. As people grow older, they tend to make less stomach acid.

*Pernicious anemia also occurs in younger people and other populations groups.

You're at higher risk for pernicious anemia if you:

* Have a family history of the condition.

* Have had part or all of your stomach removed. The stomach makes intrinsic factor, a protein that helps your body absorb vitamin B12.

* Have certain autoimmune disorders that involve the endocrine glands, such as Addison's disease, type 1 diabetes, Graves' disease, and vitiligo. Research suggests a link may exist between these autoimmune disorders and pernicious anemia that's caused by an autoimmune response.

* Have had part or all of your small intestine removed. The small intestine is where vitamin B12 is absorbed.

* Have certain intestinal diseases or disorders that prevent your body from properly absorbing vitamin B12. Examples include Crohn's disease and intestinal infections.

* Take medicines that prevent your body from properly absorbing vitamin B12. Examples of such medicines include antibiotics and certain seizure medicines.

* Are a strict vegetarian who doesn't eat any animal or dairy products and doesn't take a vitamin B12 supplement, or if you eat poorly overall.

*Above information found at U.S. Department of Health & Human Services * National Institutes of Health

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Jack Shea
Healthy Living Resources
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